Korean J Med.
2015 Jun;88(6):719-723. 10.3904/kjm.2015.88.6.719.
A Case of Small Cell Carcinoma of the Maxillary Sinus with Distant Metastasis
- Affiliations
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- 1Department of Internal Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea. miongsok@catholic.ac.kr
- 2Department of Pathology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.
- 3Department of Otorhinolaryngology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.
- 4Department of Radiation Oncology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.
- KMID: 2269089
- DOI: http://doi.org/10.3904/kjm.2015.88.6.719
Abstract
- Primary small cell carcinoma of the paranasal sinuses is extremely rare. It is aggressively locally invasive, with high recurrence and metastatic rates. A combination of systemic chemotherapy and locoregional treatment, such as radiotherapy, is currently recommended based on the treatment of small cell carcinoma of lung. We report a case of small cell carcinoma originating from the maxillary sinus with distant metastasis at the time of diagnosis. The patient had a good initial therapeutic response to etoposide-cisplatin chemotherapy, but the cancer progressed after the sixth cycle of chemotherapy and the prognosis was poor.
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