Korean J Otorhinolaryngol-Head Neck Surg.  2012 Nov;55(11):717-720. 10.3342/kjorl-hns.2012.55.11.717.

A Case of Metastatic Renal Cell Carcinoma to the Maxillary Sinus Treated with Tyrosine Kinase Inhibitor

• Kim YH
• Kim JE
• Park S
• Jang TY

• KMID: 2277428
• DOI: http://doi.org/10.3342/kjorl-hns.2012.55.11.717

Abstract

Renal cell carcinoma is a rare metastatic malignant neoplasm of the paranasal sinus. The clinical picture and radiologic findings might sometimes be insufficient to suspect metastatic renal cell carcinoma. Therefore, the definite diagnosis should be made according to the result of intraoperative biopsy. Recently, tyrosine kinase inhibitor, sunitinib, is considered as an effective agent in the treatment of metastatic renal cell carcinoma. We report a case of 69-year-old patient with metastatic renal cell carcinoma of the right maxillary sinus with accompanying fungal sinusitis. After 6 times of chemotherapy with sunitinib malate, there was no sign of recurrence or local advancement of the tumor during the 1-year follow-up period.

Keyword

Maxillary sinus neoplasms; Metastasis; Paranasal sinus; Renal cell carcinoma; Sunitinib

MeSH Terms

Aged
Biopsy
Carcinoma, Renal Cell
Follow-Up Studies
Humans
Indoles
Maxillary Sinus
Maxillary Sinus Neoplasms
Neoplasm Metastasis
Protein-Tyrosine Kinases
Pyrroles
Recurrence
Sinusitis
Tyrosine
Indoles
Protein-Tyrosine Kinases
Pyrroles
Tyrosine