Korean J Med.
2015 Sep;89(3):265-270. 10.3904/kjm.2015.89.3.265.
Recent Update in Diabetic Nephropathy
- Affiliations
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- 1Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. nhkendo@gmail.com
- KMID: 2268996
- DOI: http://doi.org/10.3904/kjm.2015.89.3.265
Abstract
- Diabetic nephropathy is the leading cause of end-stage renal disease, and is associated with increased risk of cardiovascular disease. Optimal control of blood glucose and blood pressure based on the blockade of renin-angiotensin system is the standard of care for the prevention and treatment of diabetic nephropathy. Regardless of these therapies, the prevalence of diabetic nephropathy continues to increase, highlighting the need for additional therapies. Diabetes affects the progression of kidney disease through a variety of mechanisms; several new therapeutic agents targeting these pathways have been developed, with currently being evaluated in clinical trials.
