Korean J Med.  2013 Feb;84(2):299-302.

A Case of Lung Disease and Vertebral Osteomyelitis Due to Nontuberculous Mycobacteria in a Kidney Transplant Recipient

Affiliations
  • 1Division of Nephrology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. wooseong.huh@samsung.com
  • 2Division of Pulmonology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Abstract

Nontuberculous mycobacteria (NTM) infections in kidney transplant recipients (KTR) are rare. We describe here a 52-year-old female with vertebral osteomyelitis caused by NTM, who received a kidney transplant 5 years earlier. She had been diagnosed with NTM lung disease 1 year prior. NTM therapy was delayed due to esophageal candidiasis. Mycobacterium intracellulare was isolated from sputum and bone tissue. The pattern of drug-susceptibility testing in both specimens was identical. NTM vertebral osteomyelitis due to direct inoculation is rare, and was in this case a disseminated NTM disease. The subjective symptoms resolved after 4 months of NTM treatment. This suggests that early NTM treatment is important for KTRs who have NTM disease during immunosuppressive therapy.

Keyword

Lung disease; Nontuberculous mycobacteria; Kidney transplantation; Osteomyelitis

MeSH Terms

Bone and Bones
Candidiasis
Female
Humans
Kidney
Kidney Transplantation
Lung
Lung Diseases
Mycobacterium avium Complex
Nontuberculous Mycobacteria
Osteomyelitis
Sputum
Transplants
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