Korean J Med.  2013 Jul;85(1):15-21.

Effects of Antiplatelet Drugs in Cardiovascular Prevention

• Lee HY

Abstract

Hypertension and atherosclerosis are associated with a prothrombotic or hypercoagulable state, as evident by abnormalities of haemostasis, platelets and endothelial function. Therefore, in high risk hypertensive patients, use of antiplatelet agent might be beneficial in preventing thrombotic complication such as myocardial infarction and ischemic stroke. Aspirin 100 mg daily is recommended for hypertensive patients who have one of the following categories: secondary prevention +/- cardiovascular complications, primary prevention having one of risk factors such as age > 50 years + target organ damage, a 10-year CHD risk > 15%, or type II diabetes mellitus. However, it should kept in mind that aspirin treatment be initiated after stabilization of blood pressure < 150/90 mmHg.

Keyword

Hypertension; Antiplatelet; Aspirin

MeSH Terms

Aspirin
Atherosclerosis
Blood Platelets
Blood Pressure
Diabetes Mellitus
Humans
Hypertension
Myocardial Infarction
Platelet Aggregation Inhibitors
Primary Prevention
Risk Factors
Secondary Prevention
Stroke
Aspirin
Platelet Aggregation Inhibitors