Korean J Community Nutr.  2012 Apr;17(2):243-257. 10.5720/kjcn.2012.17.2.243.

The Relationship between beta-cell Function and Nutrient Intakes in Korean Adult: Using 4th Korea National Health and Nutrition Examination Survey 2009

• Lee YM
• Chung HK
• Kimm H
• Jee SH

• KMID: 2267400
• DOI: http://doi.org/10.5720/kjcn.2012.17.2.243

Abstract

The purpose of this study was to evaluate pancreatic beta-cell function of Korean adult and to examine the associations between beta-cell function and nutrient intakes. Data were analyzed for 1,917 male and 2,885 female subjects older than 30 years using 'The Forth Korean National Health and Nutrition Survey in 2009'. We calculated HOMA beta-cell (The homeostasis model assessment of beta-cell function) using fasting glucose and fasting insulin for assessing beta-cell function. Subjects were divided into HHG (High HOMA beta-cell Group) or LHG (Low HOMA beta-cell Group) according to median of HOMA beta-cell, and then nutrient intakes were compared between two groups. In the entire study population, HHG showed lower percent of carbohydrate intakes (p < 0.05), and higher fat (p < 0.01), percent of fat (p < 0.05), vitamin A (p < 0.05), carotene (p < 0.05) and riboflavin (p < 0.05) intakes than LHG. In addition, levels of HOMA beta-cell were negatively correlated with percent of carbohydrate (beta = -0.040, p < 0.05), and positively correlated with percent of fat (beta = 0.046, p < 0.01). The subjects were then divided into two subgroups according to body mass index values, either < 23 kg/m2 (under- and normal-weight) or > or = 23 kg/m2 (over-weight and obese). Significant differences of some nutrients intakes and correlations with HOMA beta-cell were observed only in under- and normal weight subjects, but not in over-weight and obese subjects. In conclusion, high carbohydrate, lower fat and lower vitamin intakes may be related with pancreatic beta-cell dysfunction in under- and normal-weight Korean.

Keyword

beta-cell function; HOMA beta-cell; carbohydrate; fat; vitamins

MeSH Terms

Adult
Body Mass Index
Carotenoids
Fasting
Female
Glucose
Homeostasis
Humans
Insulin
Korea
Male
Nutrition Surveys
Riboflavin
Vitamin A
Vitamins
Carotenoids
Glucose
Insulin
Riboflavin
Vitamin A
Vitamins

Figure

• 

  Fig. 1 The means of HOMA β-cell level according to age and sex. HOMA β-cell: The homeostasis model assessment of β-cell function. p-values: t-test between male and female.

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