Ann Dermatol.  2009 Aug;21(3):274-276. 10.5021/ad.2009.21.3.274.

A Case of Post-zoster Eosinophilic Dermatosis

• Lee JH
• Kim HS
• Kim HO
• Park YM

• KMID: 2266289
• DOI: http://doi.org/10.5021/ad.2009.21.3.274

Abstract

Post-zoster eosinophilic dermatosis is a rare disease that occurs as an isotopic response in the region of previously healed herpes zoster. We report here on a case of post-zoster eosinophilic dermatosis that occurred 13 years after an episode of herpes zoster. A 48-year-old woman presented with several pruritic, brown papules and plaques in the same dermatome where her previous episode of herpes zoster had healed. Histopathologically, there was a dermal inflammatory cell infiltration composed of abundant eosinophils, lymphocytes and histiocytes. Based on these clinicopathologic findings, the patient was diagnosed with post-zoster eosinophilic dermatosis.

Keyword

Herpes zoster; Isotopic response; Post-zoster eosinophilic dermatosis

MeSH Terms

Eosinophils
Female
Herpes Zoster
Histiocytes
Humans
Lymphocytes
Middle Aged
Rare Diseases
Skin Diseases

Figure

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  Fig. 1 Several erythematous to brown papules and plaques with fine scales along the T10 dermatome on the right flank. Inset: a magnified view.

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  Fig. 2 (A) A biopsy specimen obtained from a representative plaque showed mild acanthosis and spongiosis in the epidermis and a perivascular inflammatory cell infiltration in the dermis (H&E, ×25). (B) The dermal perivascular inflammatory cell infiltration was composed of lymphocytes and histiocytes, along with abundant eosinophils (H&E, ×400).

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