Ann Dermatol.  2015 Apr;27(2):228-229. 10.5021/ad.2015.27.2.228.

Oral and Cutaneous Lichenoid Eruption with Nail Changes Due to Imatinib Treatment in a Chinese Patient with Chronic Myeloid Leukemia

• Zhang JA
• Yu JB
• Li XH
• Zhao L

• KMID: 2264823
• DOI: http://doi.org/10.5021/ad.2015.27.2.228

Abstract

No abstract available.

MeSH Terms

Asian Continental Ancestry Group*
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*
Lichenoid Eruptions*
Imatinib Mesylate

Figure

• 

  Fig. 1 Physical evaluation of the lichenoid drug eruption. (A) Violaceous macules and flat papules on the buttocks. (B) Large dark erythematous patches covered with thick silvery scaling on the palmaris et plantaris. (C) Erosive lesions and hemorrhagic crusts on the lips, and reticular white striations on the buccal mucosa. (D) The toenails and fingernails are thickened and yellowbrown in color.

• 

  Fig. 2 Histology of the lichenoid drug eruption. There is liquefied degeneration of the basal cells and exocytosis of mononuclear cells into the epidermis. There is a band-like infiltrate in the superficial dermis, which is predominantly composed of lymphocytes (H&E, ×200).

Reference

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