Korean J Med.  2012 Dec;83(6):813-816.

Two Cases of Hyponatremia Induced by Duloxetine for Treating Peripheral Neuropathic Pain

Affiliations
  • 1Department of Internal Medicine, Sanbon Hospital, Wonkwang University College of Medicine, Gunpo, Korea. borisoo@medimail.co.kr

Abstract

Duloxetine is a balanced serotonin and norepinephrine reuptake inhibitor available for treating peripheral neuropathic pain. The occurrence of hyponatremia as an adverse event of duloxetine treatment, but it has not yet been reported in Korea. Here, we report two cases of hyponatremia induced by duloxetine for treatment of peripheral neuropathic pain. Our findings highlight the need for special attention when using duloxetine in elderly patients taking thiazide diuretics.

Keyword

Hyponatremia; Serotonin uptake inhibitors; Duloxetine

MeSH Terms

Aged
Humans
Hyponatremia
Korea
Neuralgia
Norepinephrine
Serotonin
Serotonin Uptake Inhibitors
Sodium Chloride Symporter Inhibitors
Thiophenes
Duloxetine Hydrochloride
Norepinephrine
Serotonin
Serotonin Uptake Inhibitors
Sodium Chloride Symporter Inhibitors
Thiophenes
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