Korean J Med.  2011 Dec;81(6):797-801.

A Case of Candida Parapsilosis Infectious Arthritis in a Patient with Enteropathic Arthritis and Ulcerative Colitis

• Park HJ
• Jung SJ
• Oh TG
• Seok H
• Lee SW
• Park YB
• Lee SK

Abstract

Infectious arthritis is an important medical emergency with high morbidity. The most frequent causative organism of infectious arthritis is Staphylococcus aureus, and Candida is an uncommon pathogen. Candida arthritis has been reported to occur in seriously ill or immunocompromised patients and neonates. We report the first case of C. parapsilosis arthritis in a patient with ulcerative colitis. A 52-year-old woman was diagnosed with ulcerative colitis 1 year previously and took balsalazide. Pain and swelling in the right knee joint developed 6 months after diagnosis. She was diagnosed with enteropathic arthritis associated with ulcerative colitis and took methotrexate, sulfasalazine, and prednisolone for 3 months, but the symptoms did not improve. We finally diagnosed her with infectious C. parapsilosis arthritis by culturing the synovial fluid. The patient received amphotericin B for 6 weeks and underwent arthroscopic synovectomy. She finally experienced improvement of inflammation in the right knee joint.

Keyword

Infectious arthritis; Candida parapsilosis; Ulcerative colitis

MeSH Terms

Amphotericin B
Arthritis
Arthritis, Infectious
Candida
Colitis, Ulcerative
Emergencies
Female
Humans
Immunocompromised Host
Infant, Newborn
Inflammation
Knee Joint
Mesalamine
Methotrexate
Middle Aged
Phenylhydrazines
Prednisolone
Staphylococcus aureus
Sulfasalazine
Synovial Fluid
Ulcer
Amphotericin B
Mesalamine
Methotrexate
Phenylhydrazines
Prednisolone
Sulfasalazine