Korean J Med.
2012 May;82(5):599-602.
A Case of Acute Pancreatitis Accompanied by Multi-Organ Dysfunction after Colchicine Intoxication
- Affiliations
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- 1Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. capsulendos@gmail.com
Abstract
- Although intentional colchicine overdose is uncommon, it is a potentially life-threatening condition. Acute pancreatitis due to colchicine overdose has been reported only rarely. A 24-year-old woman ingested 30 tablets of colchicine (a total of 18 mg) with intent to commit suicide. She presented with various clinical features, including gastrointestinal toxicities, acute pancreatitis, electrolyte imbalance, myopathy, bone marrow suppression, and subsequently, hair loss. We report a case of acute pancreatitis due to colchicine intoxication, which was accompanied by various complications; the patient recovered after supportive treatment. In addition to myelosuppression and multiple-organ failure, acute pancreatitis may occur with colchicine intoxication and even worsen after recovery of other manifestations; this has not been reported previously.
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