Korean J Med.
2010 May;78(5):660-663.
A case of anaphylaxis to erythromycin
- Affiliations
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- 1Department of Internal Medicine, Medical Research Institute, Chungbuk National University College of Medicine, Chungbuk, Korea. kimmk@chungbuk.ac.kr
- 2Regional Drug Vigilence Center, Chungbuk National University College of Medicine, Chungbuk, Korea.
Abstract
- Macrolides antibiotics synthesized by Streptomyces strains are prescribed widely and seldom produce hypersensitivity reactions, even when administered topically. Consequently, they are considered very safe drugs. We report the case of a 32.year.old woman who developed anaphylactic shock after ingesting erythromycin, which she had taken twice before. The previous exposure to erythromycin, clinical findings, and a positive skin intradermal test with erythromycin (10 mg/mL) support the postulate that anaphylaxis was induced by erythromycin.