Korean J Med.
2010 May;78(5):654-659.
A case of sarcoidosis associated with acute tubular necrosis and pulmonary hemorrhage
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Chosun University, Gwangju, Korea. healthyra@chosun.ac.kr
Abstract
- Sarcoidosis is a multisystemic granulomatous disorder that commonly involves the lungs, skin, and eyes. The coexistence of sarcoidosis with a kidney disorder and pulmonary hemorrhage is extremely rare. Hypercalciuria and hypercalcemia are the most common manifestations of renal involvement, although granulomatous interstitial nephritis, glomerular disease, and obstructive uropathy also occur in sarcoidosis. Acute tubular necrosis associated with acute renal failure generally shows early remission. In Korea, no cases of sarcoidosis associated with acute tubular necrosis and pulmonary hemorrhage have been reported. Here, we describe the case of a 65-year-old man with stage 3 sarcoidosis associated with acute tubular necrosis and pulmonary hemorrhage. The patient was treated with steroid and hydroxychloroquine for approximately 1 month. Most of his symptoms improved gradually, and he has been symptom-free since then.