J Korean Rheum Assoc.  2007 Sep;14(3):251-255. 10.4078/jkra.2007.14.3.251.

A Case of Ankylosing Spondylitis Accompanying Sarcoidosis

• Choi BY
• Park YB
• Lee JH
• Ryu HJ
• Lee EY
• Lee YJ
• Lee EB
• Song YW

• KMID: 2202174
• DOI: http://doi.org/10.4078/jkra.2007.14.3.251

Abstract

Sacroiliitis is a rare manifestation in patients with sarcoidosis and there have been several case reports of ankylosing spondylitis (AS) accompanying sarcoidosis. Recently, the development of sarcoidosis has been reported in AS patients treated with tumor necrosis factor blocker. We described a 27-year-old male patient with AS and histologically proven sarcoidosis who was treated with etanercept without aggravation of sarcoidosis.

Keyword

Ankylosing spondylitis; Sarcoidosis; Etanercept

MeSH Terms

Adult
Humans
Etanercept
Male
Sacroiliitis
Sarcoidosis*
Spondylitis, Ankylosing*
Tumor Necrosis Factor-alpha
Tumor Necrosis Factor-alpha

Figure

• 

  Fig. 1. Chest CT shows bilateral mediastinal lymphadeno pathy without lung parenchymal involvement.

• 

  Fig. 2. Pelvis AP shows bilateral sacroiliitis, grade 3.

• 

  Fig. 3. Pathologic finding of hilar lymph node (H&E stain, x400) shows non-caseating granuloma. it was negative for acid fast bacilli (AFB) stain and tuberculosis polymerase chain reaction (PCR).

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