Korean J Med.
2011 Jun;80(Suppl 2):S287-S294.
A Case of Renal Angiomyolipoma with Lymph Node-Associated Elevation of Tumor Markers
- Affiliations
-
- 1Department of Internal Medicine, The Catholic University of Korea School of Medicine, Seoul, Korea. shimby@catholic.ac.kr
- 2Department of Pathology, The Catholic University of Korea School of Medicine, Seoul, Korea.
Abstract
- Angiomyolipoma is a rare, benign, mesenchymal hamartomatous neoplasm consisting of a mixture of adipose tissue, smooth muscle cells, and anomalous blood vessels. The kidney is a common origin site, but extrarenal angiomyolipoma has been reported. Simultaneous involvement of the kidney and regional lymph nodes is uncommon, and may be confused with a metastatic malignant lymph node. Lymph node involvement in angiomyolipoma represents a multifocal invasion of the tumor, rather than metastatic disease. Tumor markers usually associate with malignancy but they have sometimes been detected in benign conditions. We report a case of bilateral renal angiomyolipoma with tuberous sclerosis simultaneously involving regional lymph nodes confused with metastatic malignant lymph node enlargement due to associated elevation of serum tumor markers.
