Korean J Med.  2009 Aug;77(Suppl 1):S57-S61.

A case of cytomegalovirus colitis in a patient with liver cirrhosis

Affiliations
  • 1Department of Internal Medicine, Ewha Womans University College of Medicine, Ewha Medical Research Institute, Seoul, Korea. yook57@ewha.ac.kr
  • 2Department of Pathology, Ewha Womans University College of Medicine, Ewha Medical Research Institute, Seoul, Korea.

Abstract

Most cases of cytomegalovirus (CMV) colitis are associated with an immunocompromised status, especially with human immunodeficiency virus (HIV) infections and transplantation. It rarely occurs in immunocompetent adults. We report a rare case of CMV colitis in a patient with HBV related liver cirrhosis. A 49 year-old patient presented with lower abdominal pain and bloody diarrhea. Sigmoidoscopic examination showed multiple shallow ulcerations and severe mucosal edema. Conservative treatment for the patient including antibiotics was not effective. Repeated sigmoidoscopic examination with re-biopsy showed intranuclear inclusion bodies suggestive of CMV infection. After administration of Ganciclovir, abdominal pain and bloody diarrhea improved.

Keyword

Cytomegalovirus; Colitis; Liver cirrhosis

MeSH Terms

Abdominal Pain
Adult
Anti-Bacterial Agents
Colitis
Cytomegalovirus
Diarrhea
Edema
Ganciclovir
HIV
Humans
Intranuclear Inclusion Bodies
Liver
Liver Cirrhosis
Transplants
Ulcer
Anti-Bacterial Agents
Ganciclovir
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