Korean J Med.
2006 Jul;71(1):75-79.
A case of collagenous colitis presented with chronic diarrhea and hypokalemia
- Affiliations
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- 1Department of Internal Medicine, Ewha Womans University College of Medicine, Ewha Medical Research Institute, Seoul, Korea. jassa@ewha.ac.kr
- 2Department of Pathology, Ewha Womans University College of Medicine, Ewha Medical Research Institute, Seoul, Korea.
Abstract
- Collagenous colitis is recognized as one of the causes of chronic diarrhea accompanied with autoimmune diseases. It is a disease associated with chronic watery diarrhea and typical histologic findings of a thick subepithelial collagenous deposit on biopsy. We experienced a 75-year-old man patient with chronic watery diarrhea and mild abdominal pain for 7 years. Physical examination, laboratory and radiologic studies were unremarkable except hypokalemia. Colonoscopy disclosed mucosal atrophy, loss of submucosal vessel and altered vascularity of terminal ileum, ascending colon. Colonoscopic biopsy revealed homogenous hyaline layered collagen deposition beneath the surface epithelium and Masson's trichrome stain showed collagen deposition. We report the case of collagenous colitis with a review of literature.
