Korean J Med.  2007 May;72(5):529-535.

A case of Zollinger-Ellison syndrome: localization of gastrinoma by selective intra-arterial calcium injection

Affiliations
  • 1Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. jjjeong@catholic.ac.kr
  • 2Department of Diagnostic Radiology, The Catholic University of Korea College of Medicine, Seoul, Korea.

Abstract

Zollinger-Ellison syndrome is a very rare disease that's caused by tumor having gastrin-producing cells, and this is accompanied by hypergastrinemia leading to gastric acid hypersecretion, peptic ulcer and their complications. A 60-year-old man presented with epigastric pain and soreness he had experienced for 7 days. The endoscopic findings showed reflux esophagitis and multiple active ulcers at the antrum, the duodenal bulb and the 2nd and 3rd portions of the duodenum. The fasting serum gastrin level was markedly elevated above 1,470 pg/mL and this was consistent with the findings of gastrinoma. We confirmed the presence of gastrinoma via the abdomen CT scan and selective intra-arterial calcium injection. This is the first Korean case report of gastrinoma that was localized by selective intra-arterial calcium injection.

Keyword

Zollinger-Ellison syndrome; Gastrinoma; Selective intra-arterial calcium injection

MeSH Terms

Abdomen
Calcium*
Duodenum
Esophagitis, Peptic
Fasting
Gastric Acid
Gastrinoma*
Gastrins
Humans
Middle Aged
Peptic Ulcer
Rare Diseases
Tomography, X-Ray Computed
Ulcer
Zollinger-Ellison Syndrome*
Calcium
Gastrins
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