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Risk Factors of Multiple Gastric Polyps according to the Histologic Classification: Prospective Observational Cohort Study

Jeong CY, Kim N, Lee HS, Yoon H, Shin CM, Park YS, Kim JW, Lee DH

BACKGROUND/AIMS: The aim of this study was to determine the risk factors of multiple gastric polyps according to the histological classification of gastric polyps. METHODS: Subjects with multiple gastric polyps (at...
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Lower Risk of Gastric Atrophy and Intestinal Metaplasia in Patients with MALT Lymphoma despite Helicobacter pylori Infection

Lee SM, Cheung DY, Moon JK, Kim JI, Park SH, Kim JK

BACKGROUND/AIMS: Atrophic gastritis and intestinal metaplasia are sequential consequences of chronic Helicobacter pylori (H. pylori) infection. These conditions are well known to increase the risk of gastric adenocarcinoma development. Gastric...
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Regulation of gastrointestinal hormones during laxative activity of gallotannin-enriched extract isolated from Galla Rhois in loperamide-induced constipation of SD rats

Kim JE, Kang MJ, Choi JY, Park JJ, Lee MR, Song BR, Kim HR, Park JW, Choi HJ, Bae SJ, Hwang DY

Regulation of gastrointestinal hormones have been reported in animal models for constipation undergoing laxative therapy when administered herbal products. We undertook to investigate whether the laxative activity of gallotannin-enriched extracts...
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A Case of Multiple Endocrine Neoplasia Type 1 in Type 2 Diabetes Mellitus with Poor Glycemic Control

Lee YH, Lee YC, Lee JE, Lee SJ, Jeong SJ, Kim CH

The primary causes of uncontrolled diabetes are poor life-style, infection, ischemic heart disease and inappropriate usage of oral anti-diabetic agents and insulin. Supplementary causes are stroke, acute pancreatitis and endocrine...
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Synchronous Peripancreatic Lymph Node Gastrinoma and Gastric Neuroendocrine Tumor Type 2

Lee HW, Chung JW, Kim YJ, Kwon KA, Kim EJ, Kim KK, Lee WK, Sym SJ

A 34-year-old man was referred to our hospital with gastric polypoid lesions and biopsy-confirmed neuroendocrine tumor (NET). Computed tomography (CT) revealed a 3×3.5×8-cm retroperitoneal mass behind the pancreas, with multiple...
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Multicentric Type 3 Gastric Neuroendocrine Tumors

Lee SH, Moon D, Lee HS, Lee CK, Jeon YD, Park JH, Kim H, Lee SK

A 50-year-old woman with incidentally detected multiple gastric polyps and biopsy-proven neuroendocrine tumor (NET) was referred to our hospital. More than 10 polypoid lesions (less than 15 mm) with normal...
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Diagnostic and Treatment Approaches for Refractory Peptic Ulcers

Kim HU

Refractory peptic ulcers are defined as ulcers that do not heal completely after 8 to 12 weeks of standard anti-secretory drug treatment. The most common causes of refractory ulcers are...
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Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China

Xie XQ, Zheng KC, Wu BS, Chen TH, Lai SR, Lin ZS, Aoki K

OBJECTIVES: In Fujian Province, China, gastric cancer is one of the leading causes of mortality among all malignant tumors. Nanjing county and Minqing county are located in inland Fujian and...
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A Case of Zollinger-Ellison Syndrome in Multiple Endocrine Neoplasia Type 1 with Urolithiasis as the Initial Presentation

Lee NE, Lee YJ, Yun SH, Lee JU, Park MS, Kim JK, Kim JW, Cho JW

Zollinger-Ellison syndrome (ZES) is characterized by gastrinoma and resultant hypergastrinemia, which leads to recurrent peptic ulcers. Because gastrinoma is the most common pancreatic endocrine tumor seen in multiple endocrine neoplasia...
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Effects of the Addition of Mosapride to Gastroesophageal Reflux Disease Patients on Proton Pump Inhibitor: A Prospective Randomized, Double-blind Study

Lim HC, Kim JH, Youn YH, Lee EH, Lee BK, Park H

  • KMID: 2325770
  • J Neurogastroenterol Motil.
  • 2013 Oct;19(4):495-502.
BACKGROUND/AIMS: Proton pump inhibitors (PPIs) which are the most effective agents for the treatment of gastroesophageal reflux disease (GERD), have been known to delay gastric emptying. Mosapride has been used...
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The Effect of Co-Administration of Rebamipide on the Expression of Serum Gastrin in Long-term Proton Pump Inhibitor Users: A Prospective Pilot Study

Im EJ, Kim BW, Kim JS, Lee HM, Kim JI, Kang BK, Ji JS, Lee BI, Choi H

BACKGROUND/AIMS: In one animal study, co-administration of rebamipide with proton pump inhibitors (PPIs) could suppress hypergastrinemia but there have been no such reports on humans. The aim of this study...
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A Case of ACTH-producing Pancreatic Neuroendocrine Tumor Presenting with Cushing Syndrome

Yeum SC, Won JH, Byun DW, Jeen YM, Park HK

  • KMID: 2317671
  • Soonchunhyang Med Sci.
  • 2012 Dec;18(2):159-162.
Pancreatic neuroendocrine tumors are rare neoplasm arising from pancreatic islet cells. Occasionally they are functioning tumors secreting a variety of hormones such as insulin, gastrin, glucagon, and vasoactive intestinal peptides....
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Influence of Exposure to Extremely Low Frequency Magnetic Field on Neuroendocrine Cells and Hormones in Stomach of Rats

Hong ME, Yoon KH, Jung YY, Lee TJ, Park ES, Sohn UD, Jeong JH

Extremely low frequency magnetic fields (ELF-MF) have the ability to produce a variety of behavioral and physiological changes in animals. The stomach, as the most sensitive part of the neuroendocrine...
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A case of Zollinger-Ellison syndrome with MEN-1

Kong YH, Kim YD, Han KH, Lee SH, Jung WJ, Jang HJ, Cheon GJ

  • KMID: 2259099
  • Korean J Med.
  • 2010 Sep;79(3):289-294.
Zollinger-Ellison syndrome (ZES) is a clinical syndrome caused by excessive gastric acid secretion by gastrinoma, characteristically causing peptic disease and/or gastroesophageal reflux disease. Approximately one third of patients with gastrinoma...
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The Role of Serum Pepsinogen and Gastrin Test for the Detection of Gastric Cancer in Korea

Kim N

  • KMID: 2333663
  • J Korean Gastric Cancer Assoc.
  • 2009 Sep;9(3):78-87.
Serum pepsinogen (sPG) is a marker of gastric mucosal atrophy, a condition that has been associated with an increased risk of gastric neoplasia. A low sPGI level and a low...
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Search for Materials that Influence Human Medullary Thyroid Carcinoma Cell Proliferation

Shin HW, Jang HW, Kim KS, Lee JI, Park JY, Kim SW, Min YK, Lee MS, Lee MK, Kim KW, Chung JH

BACKGROUND: Surgical excision is the only effective treatment of medullary thyroid carcinoma (MTC) and there is no certain treatment for recurrence or distant metastasis. Materials that influence MTC cell proliferation...
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Distribution and ontogeny of gastrin- and serotonin-immunoreactive cells in the proventriculus of developing chick, Gallus gallus domestica

Aksoy A, Cinar K

The ontogeny and distribution of gastrin- and serotonin-immunoreactive (IR) cell in the proventriculus of chicks (Gallus gallus domestica, n = 60) in different growth periods was examined immunohistochemically using antisera...
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Influence of Long-term Gastric Acid Suppression Therapy on the Expression of Serum Gastrin, Chromogranin A, and Ghrelin

Chang YW

  • KMID: 1062817
  • Korean J Gastroenterol.
  • 2009 Feb;53(2):126-128.
No abstract available.
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Influence of Long-term Gastric Acid Suppression Therapy on the Expression of Serum Gastrin, Chromogranin A, and Ghrelin

Kim BW, Lee BI, Kim HK, Cho YS, Chae HS, Lee HK, Kim HJ, Han SW

  • KMID: 1062810
  • Korean J Gastroenterol.
  • 2009 Feb;53(2):84-89.
BACKGROUND/AIMS: Long-term use of proton pump inhibitor (PPI) induces hypergastrinemia, which results from the suppression of gastric acid secretion. Hypergastrinemia causes enterochromaffin-like (ECL) cell hyperplasia, which is a predisposing factor...
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The Relationship of Gastrin, Pepsinogen, and Helicobacter pylori in Erosive Reflux Esophagitis

Kwon JH, Chung IS, Son HS, Park JM, Cho YK, Lee IS, Kim SW, Choi MG

  • KMID: 1112574
  • Korean J Gastroenterol.
  • 2008 Mar;51(3):159-166.
BACKGROUND/AIMS: Helicobacter pylori (H. pylori) infection is known as a major cause of atrophic gastritis and is associated with serum gastrin, pepsinogen, and gastric acid secretion. There is still a...
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