Korean J Neurogastroenterol Motil.  2004 Jun;10(1):43-48.

The Frequency of Post-infectious Irritable Bowel Syndrome (PI-IBS) in Patients with Acute Diarrhea and a Comparison with Colonoscopic Findings

• Lee JS
• Jung SA
• Kim SE
• Shim KN
• Kim DY
• Yoo K

Abstract

BACKGROUND/AIMS
This study measured the prevalence of irritable bowel syndrome (IBS) in persons who had previously visited our hospital for acute diarrhea and had undergone a colonoscopy, and evaluated the clinical and colonoscopic findings according to the presence of post-infectious IBS (PI-IBS).
METHODS
Telephone interviews were conducted with 129 patients (54%), selected from 236 patients with acute diarrhea who had colonoscopy from January, 2001 to September, 2002. The diagnosis of IBS was based on Rome II criteria. The clinical and colonoscopic findings at the time of acute diarrhea were analyzed from the patients' charts.
RESULTS
The frequencies of IBS and of changed bowel habit in the interviewed patients were both 11% (14/129. Logistic regression analysis showed that positive bacterial culture (odds ratio, 2.7; 95% CI, 2.5 to 3.3), presence of endoscopic colitis (odds ratio, 2.9; 95% CI, 2.3 to 3.2), wider extent (odds ratio, 1.8; 95% CI, 1.1 to 3.2) and more severe colitis (odds ratio, 1.7; 95% CI, 1.2 to 2.5) were statistically significant factors of increased prevalence of IBS, while age, gender, leukocytosis, and elevated CRP were not.
CONCLUSIONS
Based on the above results, clinicians should consider the possibility of future PI-IBS particularly in patients with acute diarrhea when it is coupled with positive bacterial culture or colonoscopic findings of severe endoscopic colitis.

Keyword

Irritable bowel syndrome; Colitis

MeSH Terms

Colitis
Colonoscopy
Diagnosis
Diarrhea*
Humans
Interviews as Topic
Irritable Bowel Syndrome*
Leukocytosis
Logistic Models
Prevalence