Korean J Nephrol.  1997 Jun;16(2):369-373.

A Case of Henoch-Sch nlein Purpura Complicated with Nephrotic Syndrome and Spontaneous Bacterial Peritonitis in Patient with Stomach Cancer

• Kim YS
• Kim HK
• Won NH

Abstract

Henoch-Sch nlein purpura(HSP) occurs frequently in childhood and is a few occurrence in adults. The occurrence of nephrotic syndrome is rare in HSP patients and the association of renal disease with HSP is very important to prospect longterm clinical outcome. The causes of HSP have been diversely reported such as foods, drugs, sensitivity to infections, vaccination, insect bite, cold exposure etc and recently immune complex is studing as representative cause of HSP, but nothing is verified of definite mechanism of HSP until now. The occurrence of HSP associated with cancer has been rarely reported in the literature but there is no report in Korea. The patient was 31 year-old woman with stomach cancer who was operated in our hospital. 5 months after operation of stomach cancer, the massive proteinuria, generalized edema were developed and thereafter abdominal pain, generalized purpuric lesion on extremities were also occurred. We have done kidney biopsy and biopsy findings were compatible with HSP pathologically. After administration of prednisolone, spontaneous bacterial peritonitis was occurred suddenly, patient was recovered after ceasation of administration of prednisolone and proper antibiotic therapy but patient died of cachexia 3 months after diagnosis of HSP. We report a case of HSP presenting as nephrotic syndrome in patient with stomach cancer and complicated with spontaneous bacterial peritonitis.

Keyword

stomach cancer; Henoch-Sch nlein purpura; spontaneous bacterial peritonitis; nephrotic syndrome

MeSH Terms

Abdominal Pain
Adult
Antigen-Antibody Complex
Biopsy
Cachexia
Diagnosis
Edema
Extremities
Female
Humans
Insect Bites and Stings
Kidney
Korea
Nephrotic Syndrome*
Peritonitis*
Prednisolone
Proteinuria
Purpura*
Stomach Neoplasms*
Stomach*
Vaccination
Antigen-Antibody Complex
Prednisolone