Korean J Nephrol.  2004 Jul;23(4):649-654.

A Case of Idiopathic Retroperitoneal Fibrosis with Acute Renal Failure

• Lee KH
• Han SW
• Yun YW
• Wang JK
• Park SH
• Park US
• Won YW
• Oh YH
• Park YW
• Kee CS
• Kim HJ

Abstract

Retroperitoneal fibrosis is proliferation of fibrous tissue with inflammatory process in retroperitoneal cavity. It is relatively rare disease that has been reported less than 20 cases in Korea until now. Idiopathic type is more frequent but secondary type is increasing nowadays. Secondary causes include drugs, infections, and leakage of blood or urine, malignancies, connective tissue diseases, etc. Recent studies suggest the relationship between retroperitoneal fibrosis and autoimmunity to own vascular or lipoid tissue. It can cause compression and obstruction of ureter, abdominal aorta, hypertension and finally collapse of renal function. Surgical procedure and immunosuppressive therapy consist of mainstay of management. Corticosteroid therapy may reduce inflammation and reverse fibrosis. Retroperitoneal fibrosis is thought to have some reVersible components in early stage. Corticosteroid may be used as initial therapy but more studies should be performed. We report a case of idiopathic retroperitoneal fibrosis with acute renal failure improved with ureter stent insertion and steroid therapy.

Keyword

ldiopathic retroperitoneal fibrosis; Acute renal failure; Steroid therapy

MeSH Terms

Acute Kidney Injury*
Aorta, Abdominal
Autoimmunity
Connective Tissue Diseases
Fibrosis
Hypertension
Inflammation
Korea
Rare Diseases
Retroperitoneal Fibrosis*
Stents
Ureter