Korean J Nephrol.  2006 Mar;25(2):305-309.

A Case of Ganglioneuroma in a Patient with Gross Hematuria

• Oh SH
• Kim OK
• Shin MH
• Bae EH
• Ma SK
• Kim SW
• Kim NH
• Choi KC
• Kang TW
• Kwon DD

Abstract

Ganglioneuroma is a rare benign neoplasm that originates from the neural crest tissue and is characterized histologically by the composition of mature ganglion cells and Schwann's cells. Its definitive diagnosis is achieved by histological examination and most ganglioneuromas arise in the posterior mediastinum followed by the retroperitoneum. Due to the slow growth of the tumor, it may be incidentally detected in imaging studies for unrelated reasons and most of them are clinically silent. Recently a 18-year-old man visited Chonnam National University Hospital because of intermittent gross hematuria. We tentatively diagnosed him as renal cyst or retroperitoneal benign cystic tumor by abdominal CT and MRI, however biopsy result of surgically resected tumor showed that it contained Schwann's cells and mature ganglion cells, thus we confirmed the diagnosis of retroperitoneal ganglioneuroma. To our best knowledge, this is the first reported case of retroperitoneal ganglioneuroma with gross hematuria in Korea, so we report the case with reviews of other literatures.

Keyword

Ganglioneuroma; Retroperitoneal space; Gross hematuri

MeSH Terms

Adolescent
Biopsy
Diagnosis
Ganglion Cysts
Ganglioneuroma*
Hematuria*
Humans
Jeollanam-do
Korea
Magnetic Resonance Imaging
Mediastinum
Neural Crest
Retroperitoneal Space
Tomography, X-Ray Computed