The Prevalence and the Associated Disorders of Chronic Kidney Disease in Subjects with Health Check-Up

Chin, Ho Jun; Oh, Kook Hwan; Oh, Yoon Kyu; Na, Ki Young; Joo, Kwon Wook; Lim, Chun Soo; Kim, Yonsu; Chae, Dong Wan; Ahn, Curie; Han, Jin Suk; Lee, Jung Sang; Kim, Suhnggwon

Abstract

PURPOSE: The prevalence of chronic kidney disease (CKD) is increasing in Korea. Considerable resources have been consumed for patients with CKD. This study investigated the prevalence, the associated disorders, and the awareness of CKD and the current status of appropriate control for blood pressure and blood sugar in subjects with CKD.
Methods
We included 14,856 subjects who underwent a health check-up in Seoul National University Bundang Hospital during the last 2 years. We selected K/DOQI guideline of CKD. We used the modified MDRD equation to estimate the glomerular filtration rate (eGFR).
RESULTS
The mean eGFR was 83.3 mL/min/1.73m(2) and it decreased with aging at the rate of 5 (mL/ min/1.73m(2))/10 years. The prevalences of CKD stage 1, stage 2, and stage more than 3 were 3.2%, 9.4%, and 3.5%, respectively. The prevalence of CKD was higher in subjects with hypertension or diabetes mellitus than in subjects without it. The CKD was associated with disorders of hypertension, cardiovascular diseases, hyperuricemia, hyperphosphatenemia, hyperkalemia, and hypertriglyceridemia. The prevalence of reported kidney disease was only 6.5% in subjects with eGFR less than 60 mL/min/1.73m(2). The frequency of adequate control of blood pressure and blood sugar in subjects with CKD was lower than in subjects without CKD.
Conclusion
The subjects were rarely aware of CKD whereas the frequencies of CKD and the associated diseases were considerably high. We have to pay more attention to diagnose and treat the CKD.