Korean J Blood Transfus.  1996 Dec;7(2):139-145.

Experience of Concurrent Collection of Plosrno During a Ploteletpheresls

• Kim IT
• Lee KN
• Lim CS
• Kim YK

Abstract

BACKGROUND
There has been rapid increase in demand for fresh frozen plasma and its derivatives in Korea. It may be due to active therapy by the clinicians especially hematologic and coagulopathy areas. So, now, the plasma is lack of supply of full demand. So, We studied the concurrent collection procedure of plasma during a plateletpheresis for the purpose of plasma supply.
METHODS
Over three month period from January 1996 to March 1996, we introduced a program of concurrent collection of plasma (CCP) during plateletpheresis at Korea University Guro Hospital, in which the additional plasma are collected for preparation of FFP. Donors were enrolled in our 62 volunteer plateletpheresis. The 31 volunteers (group I) were done plateletphersis only, another volunteers (group II) were done CCP. We compared the platelet concentrate volume, to the characteristics of donor's condition and the adverse reaction during plateletpheresis between two groups.
RESULTS
Before the plateletpheresis, there were no differences in the age, weight, height, pre-platelet count between the two groups. Also there were no adverse reactions through the procedure, such as perioral paresthesia, hypotension, hyperventilataion, chills, nausea and vomiting. The mean platelet count per unit did not show significant differences between two groups. In group 1, the mean platelet concentrate volume was 300 mL, yield was 4.5 x 1011 and group II, the volume was 315 mL, the yield was 5.1 x 1011 and the fresh plasma volume was 223 mL.
CONCLUSION
We have experienced the concurrent collection procedure of plasma during a plateletpheresis from 31 volunteers without main adverse reactions.

MeSH Terms

Blood Platelets
Chills
Humans
Hypotension
Korea
Nausea
Paresthesia
Plasma
Plasma Volume
Platelet Count
Plateletpheresis
Tissue Donors
Volunteers
Vomiting