Korean J Nephrol.  2007 Nov;26(6):748-752.

Interstitial Nephritis and IgA Nephropathy in a Patient with Acute Hepatitis A

Affiliations
  • 1Department of Internal Medicine, Seoul National University College of Medicine, Korea.
  • 2Department of Internal Medicine, Seoul National University Boramae Hospital, Korea. yoonkyu@snu.ac.kr
  • 3Department of Pathology, Seoul National University College of Medicine, Korea.

Abstract

Hepatitis A is one of the most common infectious diseases. It is a self-limiting disease affecting the liver. Although extrahepatic manifestations are not common, a few cases associated with renal diseases have been reported. In those cases, patients presented with acute tubular necrosis, acute interstitial nephritis, IgA nephropathy, mesangioproliferative glomerulonephritis, etc. We here report a case of interstitial nephritis and IgA nephropathy associated with acute hepatitis A. A previously healthy 31-year old woman was admitted with an acute hepatitis A, which was confirmed by IgM anti-hepatitis A antibody. Acute renal failure was developed and hemodialysis was urgently required. The patient had acute interstitial nephritis and IgA nephropathy diagnosed by kidney biopsy. Liver and kidney functions gradually recovered their normal conditions.

Keyword

Hepatitis A; Acute renal failure; Interstitial nephritis; IgA nephropathy

MeSH Terms

Acute Kidney Injury
Adult
Biopsy
Communicable Diseases
Female
Glomerulonephritis
Glomerulonephritis, IGA*
Hepatitis A*
Hepatitis*
Humans
Immunoglobulin A*
Immunoglobulin M
Kidney
Liver
Necrosis
Nephritis, Interstitial*
Renal Dialysis
Immunoglobulin A
Immunoglobulin M
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