Korean J Nephrol.
2009 Sep;28(5):490-495.
A Case of Primary Renal Amyloidosis with Fulminant Hepatic Failure
- Affiliations
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- 1Department of Internal Medicine, Sungkyunkwan University Collage of Medicine, Samsung Hospital, Masan, Korea. chaecho@kornet.net
Abstract
- We report the case of a patient with primary renal amyloidosis, who was progressed to fulminant hepatic failure. A 68-year-old man visited our hospital for evaluation of anorexia, weight loss and hepatomegaly. Laboratory examination revealed proteinuria and azotemia. He was confirmed to have primary amyloidosis by renal biopsy. His renal function progressed to deteriorate rapidly with marked deterioration of liver function with cholestasis. Peritoneal dialysis and steroid therapy were started for reduction of urine output and rapid progression of azotemia, and aggravation of liver function. Azotemia was improved after peritoneal dialysis but the liver function worsened leading to hepatic failure, causing death. If jaundice has progressed in any patients with primary amyloidosis, liver transplantation and stem cell transplantation should be considered for preparation of hepatic failure.
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