Korean J Med.  2001 Mar;60(3):260-265.

A case of primary T cell lymphoma of the liver presented as FUO

• Kim TH
• Yoon HJ
• Kim MI
• Kim JH
• Kim SY
• Cho KS
• Jang YW
• Park YK
• Lee J
• Lee DH
• Lee SM

Abstract

Primary non-Hodgkin's lymphoma of the liver, an organ normally devoid of a native lymphoid tissue, is very rare. We report a case of primary hepatic T-cell lymphoma in a 18-year-old girl, with review of literature. The pateint admitted with fever for 5 months. The ultrasonography revealed a 10 x 7 cm sized mass in the left lobe of the liver. On abdominal CT, the mass was poorly enhancing and low attenuated. On MRI, the signal intensity of the mass was low in T1 weighted image, heterogeneously high in T2 weighted image, and peripherally enhanced in contrast enhancing T1 weighted image. The biopsy specimen obtained by laparatomy showed anaplastic tumor. The malignant cells were positive for T-cell lineage (CD3, CD44, CD45RO). There was no evidence of the lymphoma in other regions. The patient was treated with CHOP (cyclophosphamide, adriamycin, vincristine and prednisolone) chemotherapy without objective response. The patient died of sudden cardiogenic shock.

Keyword

Lymphoma; T-cell; Hepatic; Fever of unknown origin

MeSH Terms

Adolescent
Biopsy
Doxorubicin
Drug Therapy
Female
Fever
Fever of Unknown Origin
Humans
Liver*
Lymphoid Tissue
Lymphoma
Lymphoma, Non-Hodgkin
Lymphoma, T-Cell*
Magnetic Resonance Imaging
Shock, Cardiogenic
T-Lymphocytes
Tomography, X-Ray Computed
Ultrasonography
Vincristine
Doxorubicin
Vincristine