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Predictors of Diagnostic Contributions and Spontaneous Remission of Symptoms Associated with Positron Emission Tomography with Fluorine-18-Fluorodeoxy Glucose Combined with Computed Tomography in Classic Fever or Inflammation of Unknown Origin: a Retrospective Study

Tsuzuki S, Tsuzuki S, Watanabe A, Watanabe A, Iwata M, Iwata M, Toyama H, Toyama H, Terasawa T, Terasawa T

Background: In patients with fever or inflammation of unknown origin (fever of unknown origin [FUO] or inflammation of unknown origin [IUO], respectively), expert consensus recommends the use of positron emission...
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Fever of Unknown Origin: An Overview of the Diagnostic Approach

Kim EJ

Although fever of unknown origin (FUO) was first defined in 1961, it remains a diagnostic challenge. The revised 1991 definition categorized FUO into classic FUO, nosocomial FUO, neutropenic FUO, and...
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Adult-onset Still's Disease as the First Manifestation of Cerebral Infarction: a Case Report

Choi JK, Seo YJ, Kim DY

Adult-onset Still's disease (AOSD) is a rare systemic febrile disorder of unknown etiology. AOSD is characterized by spiking fever, arthralgia, sore throat, skin rash, and multi-organ involvement but is difficult...
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Outcome in Patients with Fever of Unknown Origin whose ¹⁸Fluoro-Deoxyglucose Positron Emission Tomography/Computerized Tomography Finding is Non-Diagnostic

Kim T, Park J, Choo EJ, Jeong H, Jeon CH, Hwang JP, Park JM

Prognosis has not been known for patients with fever of unknown origin (FUO) whose ¹⁸fluoro-deoxyglucose (¹⁸F-FDG) positron emission tomography/computerized tomography (PET/CT) finding is non-diagnostic. A total of eight patients with...
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Usefulness of Respiratory-Gated ¹⁸F-FDG PET/CT in Detecting Upper Abdominal Fever Focus

Bae S, Bang JI, Song YS, Lee WW

Respiratory-gated ¹⁸F-fluorodeoxygluocse (¹⁸F-FDG) PET/CT has been successfully used to better localize malignancies in the lung or upper abdominal organs. However, clinical usefulness of respiratory-gated ¹⁸F-FDG PET/CT in detection of fever...
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Etiology and clinical characteristics of fever of unknown origin in children: a 15-year experience in a single center

Kim YS, Kim KR, Kang JM, Kim JM, Kim YJ

PURPOSE: Fever is one of the most common symptoms in children. In previous studies, infectious disease was the most common cause of pediatric fever of unknown origin (FUO). The aim...
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Familial Mediterranean fever presenting as fever of unknown origin in Korea

Lee JH, Kim JH, Shim JO, Lee KC, Lee JW, Lee JH, Chae JJ

Familial Mediterranean fever (FMF) is the most common Mendelian autoinflammatory disease, characterized by uncontrolled activation of the innate immune system that manifests as recurrent brief fever and polyserositis (e.g., peritonitis,...
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FDG PET-CT in the Diagnosis of Takayasu Arteritis Presenting as Fever of Unknown Origin: A Case Report

Kim J, Oh MD

Takayasu arteritis is a chronic vasculitis involving the large vessels. At diagnosis, ischemic symptom are usually present in the affected vessels. However, fever of unknown origin (FUO) is rare as...
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Fever of Unknown Origin: An Unusual Presentation of Anti-N-Methyl-D-Aspartate Receptor Encephalitis

Hur J

Encephalitis associated with antibodies to the N-methyl-D-aspartate receptor (NMDAR) has variable clinical manifestations. Patients are often diagnosed with infectious processes because of prodromal symptoms and autonomic manifestations. Approximately 70% of...
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Advanced Erosive Gout as a Cause of Fever of Unknown Origin

Kato M, Oishi Y, Inada M, Tokuda Y

A 61-year-old man was referred to our hospital due to a 3-month history of fever of unknown origin, and with right knee and ankle joint pains. At another hospital, extensive...
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A Case of Metastatic Papillary Renal Cell Carcinoma Mimicking a Renal Abscess

Kim YW, Kim YS, Ji EY, Kim JH, Jun SY, Shin SJ, Yoon HE

Papillary renal cell carcinoma (PRCC), a histological subtype of renal cell carcinoma (RCC), accounts for approximately 10% of all RCC. Here, we report a case of metastatic RCC diagnosed unexpectedly...
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A Case of Musculoskeletal Tuberculosis Mimicking Adult-Onset Still's Disease

Cho JK, Kim MS, Shin JH, Jeong YS, Kim JW, Choi JP, Choi BY

  • KMID: 2269348
  • Korean J Med.
  • 2014 Jun;86(6):785-790.
A 46-year-old man was admitted to our hospital because of a fever of unknown origin. The patient had a skin rash, arthralgia, and hepatosplenomegaly. Laboratory tests showed leukemoid leukocytosis, a...
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A case of Wegener's granulomatosis mimicking recurrent hemophagocytic lymphohistiocytosis

Jung SM, Jung YH, Noh HJ, Woo IS, Han CW

No abstract available.
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Lower Diagnostic Value of Bone Marrow Biopsy in Children with Fever of an Unknown Origin

Yang SM, Jin SL, Kim HS, Hahn SM, Lyu CJ, Han JW

BACKGROUND: Diagnostic value of Bone marrow (BM) biopsies for fever of unknown origin (FUO) remain controversial and BM biopsies are difficult to perform in young patients. Our study aimed to...
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Case of Subacute Thyroiditis Presenting as the Cause of Fever of Unknown Origin

Kim JH, Bae KH, Choi YK, Ha IG, Park KG, Kim JG, Lee IK

  • KMID: 2267856
  • Korean J Med.
  • 2013 May;84(5):733-736.
Fever of unknown origin (FUO) is not infrequently a diagnostic dilemma for clinicians. Common infectious causes include endocarditis and abscesses in adults, and noninfectious causes include neoplasms and certain collagen...
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First Case of Bartonella henselae Bacteremia in Korea

Im JH, Baek JH, Lee HJ, Lee JS, Chung MH, Kim M, Lee SM, Kang JS

Bartonella henselae causes cat-scratch disease, bacteremia, and various focal infections. Despite the worldwide occurrence of B. henselae infections, reports in humans are rare in Korea. The clinical manifestation of all...
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Infant Langerhans Cell Histiocytosis Presented as Isolated Splenomegaly and Prolonged Fever

Shon HJ, Jung HJ, Park JE

  • KMID: 1807607
  • Clin Pediatr Hematol Oncol.
  • 2013 Oct;20(2):126-130.
The isolated spleen involvement is a rare presentation of Langerhans cell histiocytosis (LCH) and can lead to a misdiagnosis. We report a case of LCH in an infant presentated isolated...
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A Case of Acute Q Fever Hepatitis Diagnosed by F-18 FDG PET/CT

Oh M, Baek S, Lee SO, Yu E, Ryu JS

  • KMID: 2052009
  • Nucl Med Mol Imaging.
  • 2012 Jun;46(2):125-128.
A 53-year-old man with fever of unknown origin underwent F-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) as a workup for a fever of unknown origin. On presentation, he...
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A Case of Rosai-Dorfman Disease with Highly Elevated Serum Ferritin

Rew SY, Jang HC, Park KH, Ahn JS, Kim GE, Choi YD, Jung SI

Sinus histiocytosis with massive lymphadenopathy, also known as Rosai-Dorfman disease is a rare disorder characterized by proliferation of distinctive histiocytes within lymph node sinuses and lymphatics, sometimes involving extranodal sites....
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A Case of Atypical Giant Cell Arteritis Presenting as a Fever of Unknown Origin

Kang MI, Park HJ, Jeon HM, Kang Y, Lee SW, Lee SK, Park YB

Giant cell arteritis (GCA) is a systemic vasculitis predominantly found in individuals of Northern European ancestry over 50 years of age. Typically it presents with new-onset persistent headache, claudication of...
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