Korean J Med.  2004 May;66(5):521-525.

Infestation state of clonorchis sinensis in patients with pancreatobiliary diseases in ulsan: based on bile examination

• Lee KY
• Joo KR
• Kim HS
• Sin SJ
• Lee HS
• Yun TG
• Choo YI
• Park JH
• Shin JW
• Bang SJ
• Kim DH
• Park NH

Abstract

BACKGROUND: Bile examination is believed to be the most precise method for detecting Clonorchis sinensis (CS) eggs. We carried out bile examination to evaluate infestation state of CS in patients with pancreatobiliary diseases in Ulsan, known as an endemic area of CS infestation.
METHODS
We examined CS eggs in bile in three hundreds and nine patients with pancreatobiliary diseases. The bile was obtained from endoscopic nasobiliary or percutaneous transhepatic biliary drainage tubes.
RESULTS
The overall egg positive rate was 27.5% (35.3% in male, 17.6% in female). The egg positive rate was not significantly different according to the age group: 20.0% in thirties, 26.7% in forties, 24.2% in fifties, 29.9% in sixties, 36.2% in seventies and 16.7% in eighties or more. The egg positive rate according to the disease, except CS cholangitis, was not also statistically different: 32.6% in bile duct cancer, 38.5% in gallbladder cancer, 11.1% in ampulla of Vater cancer, 24.0% in pancreatic cancer, 26.4% in gallstone diseases and 12.5% in the reminder. The location of gallstone and whether CS related diseases or CS unrelated diseases did not affect the egg positive rates. The egg positive rate in patients with normal radiological findings including cholangiography was 17.0%.
CONCLUSION
This result shows that regardless of age, sex, and sorts of diseases, the infestation rate of CS was very high. On the basis of our results, it is therefore presumes that clonorchiasis is still endemic disease in Korea.

Keyword

Clonorchis sinensis; Bile; Pancreatic disease; Biliary tract disease

MeSH Terms

Ampulla of Vater
Bile Duct Neoplasms
Bile*
Biliary Tract Diseases
Cholangiography
Cholangitis
Clonorchiasis
Clonorchis sinensis*
Drainage
Eggs
Endemic Diseases
Gallbladder Neoplasms
Gallstones
Humans
Korea
Male
Ovum
Pancreatic Diseases
Pancreatic Neoplasms
Ulsan*