Korean J Med.
2004 May;66(5):478-486.
A clinical study on liver abscess over a recent 10-year period
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea. mdskc@cau.ac.kr
Abstract
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BACKGROUND: The mortality of liver abscess has remained relatively constant during this century despite earlier diagnosis, treatment of underlying causes and more aggressive antibiotics therapy. The aims of this study were to evaluate the risk factors that associated with mortality of liver abscess.
METHODS
This study was carried out retrospectively including 70 patients with liver abscess from January 1992 to August 2001. The clinical features, laboratory, imaging, and microbiologic findings, management strategy, and final outcome were studied, and prognostic factors were analyzed.
RESULTS
There were 37 males and 33 females whose ages ranged from 17 to 89 years. The mean age of the patients was 57 years, and the male to female ratio was 1.1:1. In the major part of patients, the abscess was located in the right lobe (61.4%) and single in number (78.5%). Upper abdominal pain, fever and chills were the most common symptoms, and right upper abdominal tenderness was the most common physical findings. Twenty-six percent of patients were diabetic and 40%, 10% had biliary tract disease, malignancy on presentation, respectively. A hypoalbuminemia (
Our study suggests that the factors influencing mortality in the liver abscess were hypoalbuminemia and underlying malignancy.
