Korean J Hematol.  2003 Aug;38(3):200-204.

A Case of Myeloid Blast Crisis of Atypical Chronic Myelogenous Leukemia

Affiliations
  • 1Department of Laboratory Medicine, Yeungnam University College of Medicine, Daegu, Korea. chscp@hanmail.net
  • 2Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea.
  • 3Department of Internal Medicine, Daegu Catholic University College of Medicine, Daegu, Korea.
  • 4Department of Laboratory Medicine, Chonnam University Medical School, Kwangju, Korea.

Abstract

Atypical chronic myelogenous leukemia (aCML) has dysplastic as well as proliferative features in most instance and rarely evolves to blast crisis, so it is considered as a distinct clinical entity to classical BCR-ABL (+) CML. We experienced a patient who are diagnosed aCML and transformed to myeloid blast crisis after 17 months. Monosomy 7 and deletion of 12p were found on conventional cytogenetics.

Keyword

Atypical chronic myelogenous leukemia; Myeloid blast crisis; Monosomy 7; Deletion of 12p

MeSH Terms

Blast Crisis*
Cytogenetics
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*
Monosomy
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