Blood Res.  2013 Jun;48(2):151-152. 10.5045/br.2013.48.2.151.

Pediatric chronic myeloid leukemia with B-cell lymphoid blast crisis at presentation

Affiliations
  • 1Department of Paediatric and Adolescent Oncology, The Great North Children's Hospital, Royal Victoria Infirmary, UK. drprasad_iyer@yahoo.co.uk
  • 2Cytogenetics Laboratory, Northern Genetics Service, UK.

Abstract

No abstract available.


MeSH Terms

B-Lymphocytes
Blast Crisis
Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Figure

  • Fig. 1 Blood film demonstrating chronic myeloid leukemia in lymphoid blast transformation.

  • Fig. 2 (A) Karyotype showing t(9;22)(q34;q11) Philadelphia translocation. (B) Interphase FISH, Vysis dual-fusion probe set. Green: BCR; red: ABL1; yellow: fused BCR and ABL signals corresponding to der(9) and der(22) translocation products.


Reference

1. Ries LAG, Smith MA, Gurney JG, editors. Cancer incidence and survival among children and adolescents: United States SEER Program 1975-1995. Bethesda, MD: National Cancer Institute;1999.
2. Millot F, Traore P, Guilhot J, et al. Clinical and biological features at diagnosis in 40 children with chronic myeloid leukemia. Pediatrics. 2005; 116:140–143. PMID: 15995044.
Article
3. Vardiman JW, Harris NL, Brunning RD. The World Health Organization (WHO) classification of the myeloid neoplasms. Blood. 2002; 100:2292–2302. PMID: 12239137.
Article
4. Andolina JR, Neudorf SM, Corey SJ. How I treat childhood CML. Blood. 2012; 119:1821–1830. PMID: 22210880.
Article
Full Text Links
  • BR
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr