Korean J Dermatol.  2003 Jan;41(1):135-137.

A Case of Kaposi's Sarcoma Occurring in Membranous Glomerulonephritis

• Jeong YS
• Park HY
• Park TH
• Yoo JH
• Kim KJ

Abstract

Kaposi's sarcoma is a neoplasm of multifocal origin which manifests primarily as vascular nodules in the skin and other organs. Kaposi's sarcoma in iatrogenically immunocompromised patients is the result of immunosuppressive therapy in organ-transplant recipients, autoimmune disease patients and cytotoxic chemotherapy in cancer patients. We report a case of Kaposi's sarcoma in a 50-year-old man who developed well-defined purple-colored papules and plaques on both hands and feet after prednisolone treatment for underlying membranous glomerulonephritis. The histologic finding showed abnormally proliferated and dilated vessels, vascular slits, spindle-shaped cells and extravasated erythrocytes in the dermis. He was treated with cryotherapy, and the dosage of prednisolone was reduced. Improvement was seen in 6 weeks

Keyword

Kaposi's sarcoma; Membranous glomerulonephritis

MeSH Terms

Autoimmune Diseases
Cryotherapy
Dermis
Drug Therapy
Erythrocytes
Foot
Glomerulonephritis, Membranous*
Hand
Humans
Immunocompromised Host
Middle Aged
Prednisolone
Sarcoma, Kaposi*
Skin
Prednisolone