Korean J Dermatol.
2003 Oct;41(10):1354-1358.
Removal by Mohs Micrographic Surgery and Reconstruction Using Combined Local Flaps
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- 1Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea. kychung@yumc.yonsei.ac.kr
Abstract
- Xeroderma pigmentosum is a group of dermatoses characterized by autosomal recessive inheritance, photosensitivity, photophobia, early onset freckles, and subsequent cutaneous neoplastic changes on sun-exposed areas. It is due to enzymatic defects that render the cells unable to repair UV-induced DNA damages resulting in various clinical phenotypes. A 66-year-old female patient who has been diagnosed as xeroderma pigmentosum twenty years ago developed a recurrent basal cell carcinoma on the right nasal side-wall, resulting in a large defect that comprises multiple aesthetic units, after a Mohs micrographic surgery. A combination of dorsal nasal and cheek advancement flaps with full thickness skin graft was a useful method for the reconstruction of the large nasal defect.
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