Korean J Biol Psychiatry.  2007 Feb;14(1):68-71.

Subclinical Hypothyroidism during Quetiapine Treatment: A Case Report

• Na KS
• Kim YK

Abstract

Quetiapine is an atypical antipsychotic drug with a benign side effect profile. However, recent studies have reported that thyroid dysfunction is associated with quetiapine treatment. The authors report a patient with DSM-IV bipolar I disorder who developed subclinical hypothyroidism during quetiapine treatment. The patient showed no significant clinical symptoms, but only abnormal thyroid function test findings including antithyroglobulin antibody. The abnormal thyroid function test findings were normalized after discontinuation of quetiapine. The subclinical hypothyroidism developed during quetiapine treatment may be associated with autoimmune process.

Keyword

Bipolar I disorder; Quetiapine; Atypical antipsychotics; Hypothyroidism; Thyroid gland

MeSH Terms

Diagnostic and Statistical Manual of Mental Disorders
Humans
Hypothyroidism*
Thyroid Function Tests
Thyroid Gland
Quetiapine Fumarate