J Korean Soc Endocrinol.  1994 Mar;9(1):35-38.

A Case of Subclinical Hypothyroidism Associated with Turner's Syndrome

Abstract

Recently it is known that Turner's syndrome is frequently associated with hypothyroidism. We report a case of Turner's syndrome associated with subclinical hypothyroidism. A 23-year-old female was admitted to the hospital with complaints of amenorrhea and short stature. She had a mosaicism of 45, X0/46, Xi(X_q) in the cell, cultured from the peripheral blood. The plasma thyroxine and triiodothyronine were normal and there was no clinical symptom of hypothyroidism. But the thyroid-stimulating hormone(TSH) concentration was unusually higher(184 uU/L). She has been treated with the cyclic therapy of conjugated estrogen and medroxyprogesterone, in addition to the thyroxine replacement therapy. After 2 months, the menstruation was restored and TSH was normalized.


MeSH Terms

Amenorrhea
Cells, Cultured
Estrogens
Female
Humans
Hypothyroidism*
Medroxyprogesterone
Menstruation
Mosaicism
Plasma
Thyroxine
Triiodothyronine
Turner Syndrome*
Young Adult
Estrogens
Medroxyprogesterone
Thyroxine
Triiodothyronine
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