Korean J Dermatol.  2008 Jun;46(6):846-850.

A Case of Disseminated Fusarium solani Infection ina Patient with Acute Myeloid Leukemia

Affiliations
  • 1Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea. schul@chonnam.ac.kr
  • 2Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.
  • 3Department of Laboratory Medicine, Chonnam National University Medical School, Gwangju, Korea.
  • 4Department of Pathology, Chonnam National University Medical School, Gwangju, Korea.

Abstract

Fusarium species are known as ubiquitous soil saprophytes and human skin contaminants. Infections caused by Fusarium species are increasing in frequency among immunocompromised hosts. We report a rare case of fatal disseminated infection caused by Fusarium solani in an acute myeloid leukemia patient. Skin biopsy specimen revealed multiple branched hyphae and spores in the vessel with thrombus formation, and fungal culture showed a fuzzy, whitish colony. Direct sequencing of 28S rRNA gene confirmed the isolate as Fusarium solani.

Keyword

Acute myeloid leukemia; Fusarium solani; 28S rRNA gene sequencing

MeSH Terms

Biopsy
Fusarium
Genes, rRNA
Glycosaminoglycans
Humans
Hyphae
Immunocompromised Host
Leukemia, Myeloid, Acute
Skin
Soil
Spores
Thrombosis
Glycosaminoglycans
Soil
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