Infect Chemother.
2003 Oct;35(5):321-324.
A Case of Disseminated Fusarium Infection Treated by Liposomal Amphotericin B in a Leukemic Patient
- Affiliations
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- 1Department of Internal Medicine, Korea University Medical College, Seoul, Korea. wjkim@korea.ac.kr
- 2Department of Clinical Pathology, Korea University Medical College, Seoul, Korea.
Abstract
- Fusarium spp., basically a superficial pathogen, is a newly emerging fungal pathogen of opportunistic infections in immunocompromised patients. At present, although Fusarium spp. are relatively resistant to amphotericin B, the combination of amphotericin B and surgical debridement appear to be optimal treatment for disseminated infection. Recently we experienced a 32-year-old neutropenic patient after induction chemotherapy for acute myelocytic leukemia presented with skin lesions and infiltrations in both lungs. We diagnosed with disseminated fusariosis by skin culture and successfully treated the patient with liposomal amphotericin B. We emphasize a high index of suspicion for skin lesions especially in immunocopromised patients.
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