A Clinical Study on the Efficacy of Cosmetics Containing the Ascidian tunic in Reducing Wrinkles

Sung, Hyun Chul; Jung, Hong Dae; Park, Kyung Duck; Lee, Weon Ju; Lee, Seok Jong; Kim, Do Won; Jeon, Jong Taek; Kim, Young Ju

Abstract

BACKGROUND: In the last few decades, there has been a substantial increase in the population of aged people. Aging skin is a common concern for many people these days.
OBJECTIVE
The purpose of this study was to evaluate the efficacy of cosmetics containing Ascidian tunic in reducing wrinkles.
METHODS
Cream containing the Ascidian tunic was applied to right lateral epicanthal areas of 30 subjects for 8 weeks. As control group, a placebo which does not contain the Ascidian tunic was applied to the left lateral epicanthal areas of the subjects. Skin barrier function was evaluated and skin replicas were molded on both epicanthal areas every 4 weeks. The changes of the skin wrinkles were analyzed with skin visiometer.
RESULTS
In comparison of the changes between groups treated with placebo and Ascidian tunic, there was statistically significant differences in hydration and sebum secretion. But there were no statistically significant differences in the result of R-value by visiometer.
CONCLUSION
The treatment of Ascidian tunic extract seems to be partially effective in improving wrinkles, but further study is required.