Korean J Dermatol.  2009 Jun;47(6):714-717.

Two Cases of Psoriasis Following Growth Hormone Therapy

• Heo YS
• Jeong SY
• Choi JE
• Seo SH
• Ahn HH
• Kye YC

Abstract

Growth hormone (GH) has been available for more than 4 decades for the treatment of GH deficiency. But mass production of recombinant DNA growth hormone has made GH therapy widely available for children with no GH deficiency. The use of GH therapy in children has resulted in adverse effects ranging from minor disturbances such as edema and injection site reactions to more significant, but rare events such as benign intracranial hypertension and slipped capital femoral epiphysis. Yet there has been no report in the dermatological field on skin adverse effects associated with GH therapy. We report here on 2 cases of psoriasis following GH therapy in children.

Keyword

Growth hormone; Insulin-like growth factor; Psoriasis

MeSH Terms

Child
DNA, Recombinant
Edema
Growth Hormone
Humans
Pseudotumor Cerebri
Psoriasis
Skin
Slipped Capital Femoral Epiphyses
DNA, Recombinant
Growth Hormone