Korean J Dermatol.  2010 Jun;48(6):529-532.

Successful Treatment of Steatocystoma Multiplex with OK-432 Sclerotherapy

• Park SY
• Nam HM
• Park K
• Park SD

Abstract

Steatocystoma multiplex is a hamartomatous malformation of the pilosebaceous junction and this manifests as multiple, asymptomatic, yellowish or skin-colored cystic papules and nodules located most commonly on the upper anterior portion of the trunk, upper arms and axillae. Various treatment methods such as radical excision, simple surgery, CO2 laser, cryotherapy, needle aspiration and oral retinoids have been reported, but there is currently no standard treatment. OK-432 is a biological preparation consisting of lyophilized powder containing Streptococcus pyogenes Su strain cells (group A, type3) that were treated with benzylpenicillin potassium. This has been used for sclerotherapy in patients with lymphangioma. We herein report on a case of 36-year-old female with steatocystoma multiplex on the trunk and axillary area. She was successfully treated with intralesional infusion of OK-432 after aspiration of the oily contents without recurrence or any complications such as scarring, atrophy and skin necrosis. We suggest that this sclerotherapy is a cosmetically acceptable treatment option for the multiple lesions of steatocystoma multiplex.

Keyword

OK-432; Sclerotherapy; Steatocystoma multiplex

MeSH Terms

Adult
Arm
Atrophy
Axilla
Cicatrix
Cryotherapy
Female
Humans
Infusions, Intralesional
Lasers, Gas
Lymphangioma
Necrosis
Needles
Penicillin G
Picibanil
Recurrence
Retinoids
Sclerotherapy
Skin
Sprains and Strains
Steatocystoma Multiplex
Streptococcus pyogenes
Penicillin G
Picibanil
Retinoids