Korean J Gastrointest Endosc.  2002 Jan;24(1):17-20.

A Case of Cowden's Syndrome

Affiliations
  • 1Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea. jassa@mm.ewha.ac.kr

Abstract

A 17-year-old man was referred to our hospital because of dizziness and mild dyspnea. He had a history of partial thyroidectomy due to benign mass when he was 10 year-old. His conjunctiva was anemic and acral keratosis was noted. He had a goiter and a previous surgical scar on the anterior neck just below the thyroid cartilage. Blood counts were as follows; Hb was 4.3 g/dL, WBC 5,500/mm3, PLT 366,000/ mm3. Esophagogastroduodenoscopy and colonoscopy showed esophageal acanthosis and numerous variable sized polyps in the stomach, duodenum and colon. The small bowel series showed numerous polypoid lesions in the entire small bowel. Gastric polyps revealed hamartoma and colon polyps revealed inflammatory polyp with lymphoid hyperplasia by pathologic examination. Thyroid ultrasonograph showed multiple nodules and cysts and I131 scintigraphy showed multiple cold and hot nodules in his remnant thyroid gland. We diagnosed the patient as Cowden's syndrome.

Keyword

Cowden's syndrome; Acral keratosis; Thyroid nodules; Gatrointestinal polyposis

MeSH Terms

Adolescent
Child
Cicatrix
Colon
Colonoscopy
Conjunctiva
Dizziness
Duodenum
Dyspnea
Endoscopy, Digestive System
Goiter
Hamartoma
Hamartoma Syndrome, Multiple*
Humans
Hyperplasia
Keratosis
Neck
Polyps
Radionuclide Imaging
Stomach
Thyroid Cartilage
Thyroid Gland
Thyroid Nodule
Thyroidectomy
Full Text Links
  • KJGE
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr