Korean J Med.  2009 Apr;76(Suppl 1):S31-S34.

A case of Cowden's syndrome associated with Lhermitte-Duclos disease

• Lim DK
• Kim SE
• Song JY
• Kim DH
• Kim SJ
• Park MI
• Park SJ

Abstract

Cowden's disease, or multiple hamartoma syndrome, is an uncommon autosomal dominant condition characterized by mucocutaneous lesions and systemic malignancies. Lhermitte-Duclos disease, or dysplastic gangliocytoma of the cerebellum, is a rare cerebellar lesion that can cause mass effects in the posterior fossa. It may occur sporadically, or in association with Cowden's syndrome. We report a case of Cowden's disease associated with Lhermitte-Duclos disease in a 49-year-old man who underwent a routine checkup

Keyword

Cowden disease; Lhermitte-Duclos disease

MeSH Terms

Hamartoma Syndrome, Multiple
Humans
Middle Aged