Korean J Anesthesiol.  2003 Jun;44(6):770-776. 10.4097/kjae.2003.44.6.770.

Comparison of Sevoflurane with Enflurane Anesthesia for Cesarean Section

• Suk EH
• Jeong JY
• Lee YK
• Kim YK
• Cho SK

• KMID: 2239951
• DOI: http://doi.org/10.4097/kjae.2003.44.6.770

Abstract

BACKGROUND: Sevoflurane has a low blood-gas partition coefficient, resulting in rapid induction and recovery. We compared the effects of sevoflurane with those of enflurane anesthesia on parturients and neonates during and after elective cesarean section.
METHODS
Ninety-six parturients were divided into two groups: E (enflurane, n = 47) and S (sevoflurane, n = 49). After endotracheal intubation with intravenous administration of thiopental 4 mg/kg and succinylcholine 1.5 mg/kg, anesthesia was maintained with 50% nitrous oxide in oxygen and enflurane 1 vol% or sevoflurane 1 vol%. Maternal hemodynamic parameters, blood loss, and recovery were monitored. Neonatal outcome was evaluated by Apgar scores, umblical artery blood gas analysis and acid-base status.
RESULTS
Recovery times were faster with sevoflurane anesthesia (P < 0.05). All patients in two groups developed transient hypertension and tachycardia after intubation, which returned to baseline in approximately 5 minutes. Maternal blood loss did not differ significantly between the two groups, and one patient in S group developed postoperative recall. Neonatal outcome was equally good in the two groups.
CONCLUSIONS
Parturients anesthetized with sevoflurane for cesarean section recovered more rapidly compared with enflurane without any differences in hemodynamic parameters and neonatal outcome.

Keyword

Cesarean section; enflurane; recovery; sevoflurane

MeSH Terms

Administration, Intravenous
Anesthesia*
Arteries
Blood Gas Analysis
Cesarean Section*
Enflurane*
Female
Hemodynamics
Humans
Hypertension
Infant, Newborn
Intubation
Intubation, Intratracheal
Nitrous Oxide
Oxygen
Pregnancy
Succinylcholine
Tachycardia
Thiopental
Enflurane
Nitrous Oxide
Oxygen
Succinylcholine
Thiopental