Ewha Med J.  1989 Dec;12(4):329-334. 10.12771/emj.1989.12.4.329.

Effects of Ketamine, Halothane and Enflurane on the Awareness Under N2O for Cesarean Section

• Lee GY

• KMID: 1965805
• DOI: http://doi.org/10.12771/emj.1989.12.4.329

Abstract

A major problem with general anesthesia for Cesarean section is the incidence of maternal awareness and unpleasant recall occasioned by the use small doses and low concentrations of anesthetics to minimize neonatal effect. To reduce awareness, various measures have been attempted. The purpose of study is to assess the influence of ketamine, halothane and enflurane on the maternal awareness and neonatal depression under N2O for Cesarean section. This study group consisted of 48 patients undergoing Cesarean section under general anesthesia. Anesthesia was induced by thiopental, succinylcholine chloride injected, and maintained until baby delivery with according to divided group. Group 1: thiopental, 50% N20 Group 2: thiopental, 50% N2O and ketamine(0.25mg/kg) Group 3: thiopental, 50% N2O and 0.5% halothane Group 4: thiopental, 50% N20 and 0.6% enflurane The results were as follows : 1. The incidence of awareness of 50% N2O group was 66.7%. 2. The incidence of awareness of ketamine, halothane and enflurane group was 8.3%. 3. When induction-delivery time is 8 minutes or less, there was no correlation between induction-delivery time and awareness. 4. There was no neonatal depression. The use of ketamine, halothane and enflurane appears to be effective in preventing awareness when induction-delivery time is 8 minutes or less.

Keyword

Cesarean section; Acareness; Ketamine; Halothane; Enflurane

MeSH Terms

Anesthesia
Anesthesia, General
Anesthetics
Cesarean Section*
Depression
Enflurane*
Female
Halothane*
Humans
Incidence
Ketamine*
Pregnancy
Succinylcholine
Thiopental
Anesthetics
Enflurane
Halothane
Ketamine
Succinylcholine
Thiopental