Korean J Anesthesiol.  1991 Feb;24(1):56-59. 10.4097/kjae.1991.24.1.56.

A Study on the Perioperative Changes of Creatine Kinase and Lactic Dehydrogenase

• Do SH
• Kwack KJ
• Ko H
• Ham BM

• KMID: 2239368
• DOI: http://doi.org/10.4097/kjae.1991.24.1.56

Abstract

A retrospective study was conducted to evaluate the changes in serum creatine kinase (CK) and lactic dehydrogenase (LDH) after coronary artery bypass grafting surgery. We studied 37 patients who had normal liver and kidney functions and who did not have the perioperative acute myocardial infarction. After measuring total serum LDH and isoenzyme 1 to 5, and seum CK and isoenzyme CK-MB, we compared pastoperative values to preoperative value. We also calculated the ratio of LD1 to LD2 (LD1 /LD2). Total LDH increased for postoperative 0 day, 1 day, 2 day, and 4 day. LD1, LD2 LD3 and LD4, increased for postoperative 0 day, 1 day, and 2 day, but LD5 increased for 0 day and 1 day. Total CK increased for 0 day, 1 day, and 2 day, but CK-MB did not increase postoperatively. LD1/LD2 increased at posoperative 2 day. Among the total 113 samples, the number of the cases of LD1/LD2 > 1 is 12.

Keyword

Serum creatine kinase; Serum lactic dehydrogenase; Coronary bypass

MeSH Terms

Coronary Artery Bypass
Creatine Kinase*
Creatine*
Humans
Kidney
Liver
Myocardial Infarction
Oxidoreductases*
Retrospective Studies
Creatine
Creatine Kinase
Oxidoreductases