Korean J Anesthesiol.  1995 Feb;28(2):228-233. 10.4097/kjae.1995.28.2.228.

The Analgesic Effect of Intraarticular Bupivacaine and Morphine after Arthroscopic Knee Surgery

• Lee SC
• Cho HS

• KMID: 2239167
• DOI: http://doi.org/10.4097/kjae.1995.28.2.228

Abstract

The effects of intrarticular bupivacaine(20 ml, 0.25%), morphine(1 mg in 20 ml NaCl), or combination of the two(morphine 1 mg or 2 mg in 20 ml of 0.25% bupivacaine) on postoperative analgesia after arthroscopic knee surgery were studied in randomized, prospective, double-blind trial in ASA I-II patients receiving spinal anesthesia. The pain was assessed 1, 2, 3, 4, 5, 24 and 48 hours after procedure by the visual analogue pain scale(VAS) scores, and additional analgesic requirement was recorded. There was no significant difference in VAS scores and additional analgesic requirements among groups except 5 hours after procedure. Both parameters were significantly greater in the bupivacaine-only-treated group than in the other three groups at that time. It is suggested that we'd better use morphine 1 mg in normal saline without bupivacaine after arthroscopic knee surgery to get the desirable postoperative analgesic effect.

Keyword

Intraarticular; Morphine; Bupivacaine; Postoperative Analgesia; Arthroscopic knee surgery

MeSH Terms

Analgesia
Anesthesia, Spinal
Bupivacaine*
Humans
Knee*
Morphine*
Prospective Studies
Bupivacaine
Morphine