Korean J Anesthesiol.
1996 Aug;31(2):254-261. 10.4097/kjae.1996.31.2.254.
Comparison of Butorphanol and Morphine Patient Controlled Analgesia after Gynecological Surgery
- Affiliations
-
- 1Department of Anesthesiology Samsung Medical Center, Seoul Korea.
- KMID: 2237791
- DOI: http://doi.org/10.4097/kjae.1996.31.2.254
Abstract
-
BACKGROUND: Intravenous patient controlled analgesia (IV-PCA) is a very popular and relatively safe technique due to its innate negative feedback mechanism. Morphine, the most commonly used analgesic, however, has its own drawbacks due to troublesome side effects. Narcotic agonist-antagonists are known to have ceiling effects not only to their analgesic potency, but also to their side effects. The authors studied the efficacy and incidence of side effects of Butorphanol IV-PCA for postoperative analgesia and compared these to morphine.
METHODS
38 ASA class I or II patients, undergoing gynecological surgery were randomly assigned into two groups, respectively Butorphanol and Morphine and examined hemodynamic changes, overall pain relief, patients satisfaction and the frequency of side effects. After general anesthesia, each patient randomly received loading dose of butorphanol or morphine in the recovery room and discharged to the floor with the PCA module. Upon arrival, individual patient was evaluated at predetermined time interval for 24 hours.
RESULTS
The percentage of patient satisfaction was very high in both groups. The incidence of nausea was less in butorphanol group. The incidence of other side effects was statistically insignificant.
CONCLUSIONS
Butorphanol has less incidence of side effects and comparable level of analgesia when compared to morphine. We conclude that butorphanol may be considered as a part of routine IV-PCA regimen, in postoperative pain management.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Comparison of the Effects of Morphine Versus Morphine Plus Butorphanol in Epidural Anesthesia for Postoperative Analgesia
- Comparison of Butorphanol with Morphine in Intravenous Patient Controlled Analgesia (PCA) for Postoperative Pain Relief
- Comparison of Butorphanol and Fentanyl for Patient-controlled Epidural Analgesia after Gastrectomy
- Comparison of Butorphanol and Fentanyl Administered with Bupivacaine for Patient Controlled Epidural Analgesia after Cesarean Section
- A Comparison of Butorphanol and Fentanyl Administered in Conjuction with Ketorolac in Intravenous Patient Controlled Analgesia after Total Abdominal Hysterectomy
