Korean J Anesthesiol.  1996 Dec;31(6):807-810. 10.4097/kjae.1996.31.6.807.

Bronchospasm After Intravenous Esomolol Injection with Rapid Sequence Induction for Preeclamptic Patient: Case report

• Park JH
• Park JG
• Kim JM
• Kim AR

• KMID: 2236917
• DOI: http://doi.org/10.4097/kjae.1996.31.6.807

Abstract

Esmolol is rapid ultrashort-acting, cardioselective beta1-adrenergic blocker and that is used for attenuation of acute hypertension associated with rapid sequence induction of general anesthesia. A 35-year-old severe preeclamptic patient was scheduled for elective cesarean section. After preoxygenation, anesthesia induced with using penthotal sodium 250 mg, esmolol 25 mg, and succinylcholine 62.5 mg for endotrachial intubation. We detected to increase airway resistance during manual ventilation. Breathing sound was auscultated wheezing and ronchi. And then cyanosis was developed and oxygen saturation was decreased to below 75%. After 20 min, patient's color was returned to pink and patient's self-respiratory function was good. Bronchospasm occured because that beta-adrencergic blockade with esmolol, by leaving the parasympathetic and alpha-adrencrgic influence relatively unopposed. We report bronchospasm after esmolol 25 mg was injeected for attenuation of acute hypertensive response for cesarean section of preeclamptic patient with rapid sequence induction of general anesthesia.

Keyword

Pregnancy preeclamsia; Complication bronchospasm; Pharmacology esmolol

MeSH Terms

Adult
Airway Resistance
Anesthesia
Anesthesia, General
Bronchial Spasm*
Cesarean Section
Cyanosis
Female
Humans
Hypertension
Intubation
Oxygen
Pregnancy
Respiratory Sounds
Sodium
Succinylcholine
Ventilation
Oxygen
Sodium
Succinylcholine